Process Optimization for the Pharmaceutical Industry

	"Each gram saved is a real gain and we can now perform much better in a sector where high quality is crucial." Hubert Müller, Process Engineer, Siemens Axiva GmbH.

Fundamental to pharmaceutical drug development and production is that "Every patient is special" . Strict regulatory requirements and quality control of actives, excipients, intermediates and raw materials exist to ensure that this simple edict is fulfilled. Malvern Process Systems offers particle sizing solutions that allow you to:

	Reduce time to market through improved process understanding using the same analyzer from pilot to production
	Improve process reliability through better understanding of unit operation performance in accordance with PAT
	Meet pharmaceutical industry standards and guidelines including PAT, GAMP4, CIP/SIP, 21 CFR Part 11, validation and IS
	Eliminate operator exposure to highly toxic compounds through containment
	Improve startup and shutdown performance to reduce improve yield of batch processes using high value materials

In this section

	Pharmaceutical Process Optimization - Industry Overview Around 70% of pharmaceutical drugs are consumed as the solid oral dosage type and the particle size properties of active pharmaceutical ingredients (API) and excipients play an important role in their efficacy.
	Pharmaceutical Process Optimization - Industry Concerns Economic and regulatory pressures are driving innovations in particulate processing in pharmaceutical manufacturing, such as controlling particle size through continuous, online measurement.
	Pharmaceutical Process Optimization - Analyzers and Automation Complete online and at-line particle characterization systems appropriate to the requirements of the pharmaceutical industry and unit operations.
	Pharmaceutical Process Optimization - Case Studies:
	Case study Contract Pharmaceutical Milling, Increasing the yield from valuable feed materials.
	Case study Online Control of Particle Size during Fluidised Bed Granulation.
	Case study Improving Pharma Manufacturing.